@prefix fhir: <http://hl7.org/fhir/> .
@prefix loinc: <https://loinc.org/rdf/> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix rdf: <http://www.w3.org/1999/02/22-rdf-syntax-ns#> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix sct: <http://snomed.info/id/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

# - resource -------------------------------------------------------------------

<http://fhir.nmdp.org/ig/cibmtr-reporting/Observation/Cytogenetics-Example-1> a fhir:Observation ;
  fhir:nodeRole fhir:treeRoot ;
  fhir:id [ fhir:v "Cytogenetics-Example-1"] ; # 
  fhir:meta [
     fhir:profile ( [
       fhir:v "http://fhir.nmdp.org/ig/cibmtr-reporting/StructureDefinition/cibmtr-cytogenetics"^^xsd:anyURI ;
       fhir:link <http://fhir.nmdp.org/ig/cibmtr-reporting/StructureDefinition/cibmtr-cytogenetics>
     ] ) ;
     fhir:security ( [
       fhir:system [ fhir:v "http://terminology.cibmtr.org/codesystem/transplant-center"^^xsd:anyURI ] ;
       fhir:code [ fhir:v "rc_99999" ] ;
       fhir:display [ fhir:v "99999 My Transplant Center" ]
     ] )
  ] ; # 
  fhir:text [
     fhir:status [ fhir:v "generated" ] ;
     fhir:div "<div xmlns=\"http://www.w3.org/1999/xhtml\"><p class=\"res-header-id\"><b>Generated Narrative: Observation Cytogenetics-Example-1</b></p><a name=\"Cytogenetics-Example-1\"> </a><a name=\"hcCytogenetics-Example-1\"> </a><div style=\"display: inline-block; background-color: #d9e0e7; padding: 6px; margin: 4px; border: 1px solid #8da1b4; border-radius: 5px; line-height: 60%\"><p style=\"margin-bottom: 0px\"/><p style=\"margin-bottom: 0px\">Profile: <a href=\"StructureDefinition-cibmtr-cytogenetics.html\">CIBMTR Cytogenetics Profile</a></p><p style=\"margin-bottom: 0px\">Security Label: 99999 My Transplant Center (Details: transplant-center code rc_99999 = '99999 My Transplant Center')</p></div><p><b>status</b>: Final</p><p><b>category</b>: <span title=\"Codes:{http://terminology.hl7.org/CodeSystem/observation-category laboratory}\">Laboratory</span></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 69548-6}\">Genetic variant assessment</span></p><p><b>subject</b>: <a href=\"Patient-PatientExample1.html\">Jane Doe  Female, DoB Unknown ( http://example.org/mrn#abc)</a></p><p><b>effective</b>: 2022-05-01</p><p><b>method</b>: <span title=\"Codes:{http://snomed.info/sct 426329006}\">Fluorescence in situ hybridization</span></p><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 81291-7}\">Variant ISCN</span></p><p><b>value</b>: <span title=\"Codes:{https://iscn.karger.com 47&lt;2n>,XY,-7,+8,t(9;22)(q34.1;q11.2),i(17)(q10),+der(22)t(9;22)(q34.1;q11.2)}\">47&lt;2n&gt;,XY,-7,+8,t(9;22)(q34.1;q11.2),i(17)(q10),+der(22)t(9;22)(q34.1;q11.2)</span></p></blockquote><blockquote><p><b>component</b></p><p><b>code</b>: <span title=\"Codes:{http://loinc.org 48002-0}\">Genomic source class</span></p><p><b>value</b>: <span title=\"Codes:{http://loinc.org LA6684-0}\">Somatic</span></p></blockquote></div>"^^rdf:XMLLiteral
  ] ; # 
  fhir:status [ fhir:v "final"] ; # 
  fhir:category ( [
     fhir:coding ( [
       fhir:system [ fhir:v "http://terminology.hl7.org/CodeSystem/observation-category"^^xsd:anyURI ] ;
       fhir:code [ fhir:v "laboratory" ]
     ] )
  ] ) ; # 
  fhir:code [
     fhir:coding ( [
       a loinc:69548-6 ;
       fhir:system [ fhir:v "http://loinc.org"^^xsd:anyURI ] ;
       fhir:code [ fhir:v "69548-6" ] ;
       fhir:display [ fhir:v "Genetic variant assessment" ]
     ] )
  ] ; # 
  fhir:subject [
     fhir:link <http://fhir.nmdp.org/ig/cibmtr-reporting/Patient/PatientExample1> ;
     fhir:reference [ fhir:v "Patient/PatientExample1" ]
  ] ; # 
  fhir:effective [
     a fhir:dateTime ;
     fhir:v "2022-05-01"^^xsd:date
  ] ; # 
  fhir:method [
     fhir:coding ( [
       a sct:426329006 ;
       fhir:system [ fhir:v "http://snomed.info/sct"^^xsd:anyURI ] ;
       fhir:code [ fhir:v "426329006" ] ;
       fhir:display [ fhir:v "Fluorescence in situ hybridization" ]
     ] )
  ] ; # 
  fhir:component ( [
     fhir:code [
       fhir:coding ( [
         a loinc:81291-7 ;
         fhir:system [ fhir:v "http://loinc.org"^^xsd:anyURI ] ;
         fhir:code [ fhir:v "81291-7" ] ;
         fhir:display [ fhir:v "Variant ISCN" ]
       ] )
     ] ;
     fhir:value [
       a fhir:CodeableConcept ;
       fhir:coding ( [
         fhir:system [ fhir:v "https://iscn.karger.com"^^xsd:anyURI ] ;
         fhir:code [ fhir:v "47<2n>,XY,-7,+8,t(9;22)(q34.1;q11.2),i(17)(q10),+der(22)t(9;22)(q34.1;q11.2)" ]
       ] )
     ]
  ] [
     fhir:code [
       fhir:coding ( [
         a loinc:48002-0 ;
         fhir:system [ fhir:v "http://loinc.org"^^xsd:anyURI ] ;
         fhir:code [ fhir:v "48002-0" ] ;
         fhir:display [ fhir:v "Genomic source class" ]
       ] )
     ] ;
     fhir:value [
       a fhir:CodeableConcept ;
       fhir:coding ( [
         a loinc:LA6684-0 ;
         fhir:system [ fhir:v "http://loinc.org"^^xsd:anyURI ] ;
         fhir:code [ fhir:v "LA6684-0" ] ;
         fhir:display [ fhir:v "Somatic" ]
       ] )
     ]
  ] ) . # 

# -------------------------------------------------------------------------------------