CIBMTR Reporting Implementation Guide
0.1.6 - Trial Use 1

This page is part of the CIBMTR Reporting Implementation Guide (v0.1.6: Release Draft) based on FHIR R4. This is the current published version. For a full list of available versions, see the Directory of published versions

Artifacts Summary

This page provides a list of the FHIR artifacts defined as part of this implementation guide.

Structures: Resource Profiles

These define constraints on FHIR resources for systems conforming to this implementation guide.

CIBMTR Cytogenetics Profile

CIBMTR Cytogenetics Profile to capture ISCN

CIBMTR Observation Laboratory Results: Priority Variables

CIBMTR Observation Laboratory Results: Priority Variables

CIBMTR Observation Laboratory Results Profile (us-core)

CIBMTR Observation Laboratory Results Profile (us-core)

CIBMTR Patient Profile (us-core)

CIBMTR Patient Profile for CRID assignment (us-core)

CIBMTR Additional Drugs in Peri-Transplant Period

CIBMTR Additional Drugs Given in the Peri-Transplant Period. Drugs may be given during the peri-transplant period to prevent transplant-related complications, such as liver injuries or to facilitate engraftment.

CIBMTR GVHD Prophylaxis Medication

CIBMTR GVHD Prophylaxis Medication

CIBMTR Medication (us-core)

CIBMTR Medication (us-core)

CIBMTR Medication Administration (mcode)

CIBMTR Medication Administration (mcode)

CIBMTR Medication Request (mcode)

CIBMTR Medication Request (mcode)

CIBMTR Mobilizing Agents Medication

CIBMTR Mobilizing Agents (auto only) Medication

CIBMTR Planned Post-HCT Disease Therapy Medication

CIBMTR Planned Post-HCT Disease Therapy Medication

CIBMTR Prep Regimen Medication

CIBMTR Pre-HCT Preparative Regimen (Conditioning) Medication

CIBMTR Prior Exposure Medication

CIBMTR Prior Exposure: Potential Study Eligibility Medication

Terminology: Value Sets

These define sets of codes used by systems conforming to this implementation guide.

Auto Differential panel - Blood (57023-4)

Auto Differential panel - Blood (57023-4)

CBC panel - Blood by Automated count (58410-2)

CBC panel - Blood by Automated count (58410-2)

CBC W Auto Differential panel - Blood (57021-8)

CBC W Auto Differential panel - Blood (57021-8)

CBC W Differential panel, method unspecified - Blood (69742-5)

CBC W Differential panel, method unspecified - Blood (69742-5)

CBC W Ordered Manual Differential panel - Blood (57782-5)

CBC W Ordered Manual Differential panel - Blood (57782-5)

Differential panel, method unspecified - Blood (69738-3)

Differential panel, method unspecified - Blood (69738-3)

Erythrocyte morphology panel - Blood (58408-6)

Erythrocyte morphology panel - Blood (58408-6)

GVHD ICD-10 Codes

GVHD ICD-10 Codes

GVHD SNOMED CT Codes

GVHD SNOMED CT Codes

GVHD Type Value Set

Permissible values for types of Graft vs Host Disease, from SNOMED CT and ICD-10

Disorders of hematopoietic structure

SNOMED: Disorders of hematopoietic structure

Leukocyte morphology panel - Blood (58407-8)

Leukocyte morphology panel - Blood (58407-8)

Manual Differential panel - Blood (24318-8)

Manual Differential panel - Blood (24318-8)

Platelet morphology panel - Blood (58406-0)

Platelet morphology panel - Blood (58406-0)

Presence Answer List

Permissible values for presence

CIBMTR Priority Variables Value Set (FY21)

Priority Variables for CIBMTR (FY21)

CIBMTR Priority Variables Value Set (FY22)

Priority Variables for CIBMTR (FY22)

CIBMTR Priority Variables Value Set for Epic App (FY21)

Priority Variables for Epic CIBMTR Reporting App (FY21)

RxNorm - Additional Drugs in Peri-Transplant Period

RxNorm codes for Additional Drugs in Peri-Transplant Period

RxNorm - Alemtuzumab

RxNorm codes for Alemtuzumab

RxNorm - All of Form 2400

RxNorm codes for all of Form 2400

RxNorm - Anti-Thymocyte Globulin

RxNorm codes for Anti-Thymocyte Globulin

RxNorm - Bortezomib

RxNorm codes for Bortezomib

RxNorm - Busulfan

RxNorm codes for Busulfan

RxNorm - Carmustine

RxNorm codes for Carmustine

RxNorm - Cyclophosphamide

RxNorm codes for Cyclophosphamide

RxNorm - Cytarabine

RxNorm codes for Cytarabine

RxNorm - Defibrotide

RxNorm codes for Defibrotide

RxNorm - Etoposide

RxNorm codes for Etoposide

RxNorm - Fludarabine

RxNorm codes for Fludarabine

RxNorm - GVHD Prophylaxis

RxNorm codes for GVHD Prophylaxis

RxNorm - Melphalan

RxNorm codes for Melphalan

RxNorm - Mobilizing Agents (auto only)

RxNorm codes for Mobilizing Agents (auto only)

RxNorm - Post-HCT Disease Therapy Planned

RxNorm codes for Post-HCT Disease Therapy Planned

RxNorm - Prep Regimen

RxNorm codes for Prep Regimen

RxNorm - Prior Exposure: Potential Study Eligibility

Prior Exposure: Potential Study Eligibility

RxNorm - Rituximab

RxNorm codes for Rituximab

RxNorm - Thiotepa

RxNorm codes for Thiotepa

RxNorm - Treosulfan

RxNorm codes for Treosulfan

RxNorm - Ursodiol

RxNorm codes for Ursodiol

SNOMED Myelodysplastic Diseases

The myelodysplastic syndromes (MDS) are a group of clonal hematopoietic stem cell diseases characterized by cytopenia(s), dysplasia (abnormal growth or development leading to an alteration in size, shape, and organization of the cell) in one or more of the major myeloid cell lines (WBC, RBC, and/or platelets), ineffective hematopoiesis, and an increased risk of developing acute myelogenous leukemia (AML). MDS occurs primarily in older adults, with a median age of 70 years. The majority of recipients present with symptoms related to cytopenias. Most recipients present with anemia requiring RBC transfusions.

Smear morphology panel - Blood (34994-4)

Smear morphology panel - Blood (34994-4)

Example: Example Instances

These are example instances that show what data produced and consumed by systems conforming with this implementation guide might look like.

ABOBloodGroupObservationLOINC

ABO group [Type] in Blood (883-9) with LOINC answer

ABOBloodGroupObservationSNOMED

ABO group [Type] in Blood (883-9) with SNOMED answer

ABORhObservationLOINC

ABO and Rh group [Type] in Blood (882-1) with LOINC answer

ABORhObservationSNOMED

ABO and Rh group [Type] in Blood (882-1) with SNOMED CT answer

AlbuminObservation

Albumin [Mass/volume] in Serum or Plasma

BasophilsObservation

Basophils/100 leukocytes in Blood

CMVDNAViralLoadCopiesmL

Cytomegalovirus DNA [#/volume] (viral load) in Bronchoalveolar lavage by NAA with probe detection (49349-4)

CMVDNAViralLoadIUmL

Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection (72493-0)

CMVIgAbPresenceSNOMED

Cytomegalovirus IgG Ab [Presence] in Serum or Plasma by Immunoassay (13949-3) with SNOMED CT answer

CMVIgGAbPresenceLOINC

Cytomegalovirus IgG Ab [Presence] in Serum or Plasma by Immunoassay (13949-3) with LOINC answer

CMVIgMAbPresenceLOINC

Cytomegalovirus IgM Ab [Presence] in Serum or Plasma by Immunoassay (24119-0) with LOINC answer

CMVIgMAbPresenceSNOMED

Cytomegalovirus IgM Ab [Presence] in Serum or Plasma by Immunoassay (24119-0) with SNOMED answer

Cytogenetics-Example-1

Example of ISCN report

EosinophilsObservation

Eosinophils observation, #/volume in Blood

HemoglobinObservation

Hemoglobin [Mass/volume] in Blood

LeukocytesObservation

Leukocytes observation

Medication-Cyclophosphamide-Example

Medication - Cyclophosphamide, 1 G injection

Medication-Etoposide-Example

Medication - Etoposide (Vepesid) chemo IBPB, 20MG/ML

Medication-GVHD-Prophylaxis-Example

Medication - GVHD Prophylaxis Example - Cyclosporine

Medication-Mobilizing-Agent-Example

Medication - Mobilizing Agents Example - Pegfilgrastim

Medication-Peri-Transplant-Example

Medication - Additional Peri-Transplant Example - Anti-Thymocyte gGobulin

Medication-Post-HCT-Disease-Therapy-Example

Medication - Post-HCT Disease Therapy Planned Example - Blinatumomab

Medication-Prep-Regimen-Example

Medication - Pre-HCT Preparatoive Regimen (Conditioning) Example - Pegfilgrastim

Medication-PriorExposure-Example

Medication - Prior Exposure: Potential Study Eligibility Example - Mogamulizumab

MedicationAdministration-Example1

Medication - Medication Administration example using medicationReference - Etoposide

MedicationAdministration-Example2

Medication - Medication Administration example using medicationCodeableConcept - Etoposide

MedicationRequest-Etoposide-Example

Medication Request for Etoposide (Vepesid) chemo IBPB, 20MG/ML

MetamyelocytesObservation

Metamyelocytes [Presence] in Blood

NeutrophilsObservation

Neutrophils [#/volume] in Cord blood

PatientExample1

Patient with CIBMTR CRID

PatientExample2

example using CIBMTR center number

PatientExample3

Patient with MRN and CRID, Race=White, Ethnicity=Unknown

PatientExample4

Patient with CRID and MRN, Race=Black or African American, Ethnicity=Unknown

PatientExample5

Patient with CRID & MRN, Race=Mixed, Ethnicity=Not Hispanic or Latino

PatientExample6

Patient with CIBMTR CRID